IMR Press / JIN / Volume 22 / Issue 3 / DOI: 10.31083/j.jin2203068
Open Access Original Research
Association of Dizziness-Related Handicap or Disability with Clinical Features in Patients with Early Parkinson’s Disease
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1 Department of Neurology, Soonchunhyang University Seoul Hospital, Soonchunhyang University School of Medicine, 04401 Seoul, Republic of Korea
*Correspondence: denovo78@naver.com (Kyum-Yil Kwon)
J. Integr. Neurosci. 2023, 22(3), 68; https://doi.org/10.31083/j.jin2203068
Submitted: 2 December 2022 | Revised: 15 January 2023 | Accepted: 30 January 2023 | Published: 9 May 2023
Copyright: © 2023 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.
Abstract

Background: Complaining of dizziness is common in patients with Parkinson’s disease (PD) even at the early phase of the disease. Therefore, regarding motor or non-motor symptoms, clinical implication of subjective dizziness in early Parkinsonian patients is needed to be explored. Methods: Eighty patients diagnosed with early PD (defined by disease duration of five years or less) were retrospectively enrolled for the study. Dizziness handicap inventory (DHI), the American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) Functional Level Scale (FLS), and clinical features of parkinsonian motor and non-motor symptoms using representative measurements. Results: Through simple and multiple linear regression analyses, we found that both DHI and FLS were significantly and positively correlated with postural instability/gait disorder (PIGD) score but negatively with the Montreal cognitive assessment (MoCA) score. Conclusions: We found that subjective dizziness in patients with early PD was related to not only axial symptoms of PIGD, but also global cognitive function of MoCA. Further research is required to confirm our results.

Keywords
dizziness
motor symptom
cognition
Parkinson's disease
Funding
201908018/Soonchunhyang University Research Fund
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