IMR Press / RCM / Volume 7 / Issue 3 / pii/1561344047696-176983373

Reviews in Cardiovascular Medicine (RCM) is published by IMR Press from Volume 19 Issue 1 (2018). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with MedReviews, LLC.

Open Access Case Review
Congenital Long QT Syndrome
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1 Department of Internal Medicine, Wright State University Boonshoft School of Medicine, Section of Electrophysiology, Good Samaritan Hospital, Dayton, OH
Rev. Cardiovasc. Med. 2006, 7(3), 160–165;
Published: 30 September 2006
Abstract
Long QT syndrome (LQTS) can be asymptomatic—identifiable as an incidental finding on electrocardiogram—or it can present with palpitation, syncope, seizures, or sudden cardiac death. LQTS is characterized by a prolonged QT interval, which can be associated with a specific form of polymorphic ventricular tachycardia known as torsade de pointes. Other electrocardiogram changes in LQTS include T-wave abnormalities, particularly bifid T waves, U waves, and T-wave alternans. The precipitating factors of LQTS include electrolyte abnormalities, bradyarrhythmias, medications (such as antiarrhythmic drugs, antibiotics, antipsychotics, and antihistamines), and myocardial ischemia. The authors report a case of LQTS in a 47-year-old woman with no other significant cardiac history.
Keywords
Long QT syndrome
Torsade de pointes
Sudden cardiac death
Romano-Ward syndrome
Jervell and Lange-Nielsen syndrome
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