Academic Editors: Lee Stoner, Jun Zhang, Ferdinando Carlo Sasso and Davide Bolignano
In-hospital acute kidney injury (IH-AKI) has been reported in a significant
proportion of patients with COVID-19 and is associated with increased disease
burden and poor outcomes. However, the mechanisms of injury are not fully
understood. We sought to determine the significance of race on cardiopulmonary
outcomes and in-hospital mortality of hospitalized COVID-19 patients with AKI. We
conducted a retrospective cohort study of consecutive patients hospitalized in
Grady Health System in Atlanta, Georgia between February and July 2020, who
tested positive for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
on qualitative polymerase-chain-reaction assay. We evaluated the primary
composite outcome of in-hospital cardiac events, and mortality in blacks with AKI
versus non-blacks with AKI. In a subgroup analysis, we evaluated the impact of
AKI in all blacks and in all non-blacks. Of 293 patients, effective sample size
was 267 after all exclusion criteria were applied. The mean age was 61.4