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- Academic Editor
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†These authors contributed equally.
Background: To compare the oncological outcomes of Chinese patients
with International Federation of Gynecology and Obstetrics (FIGO) 2018 stage IIIC
cervical cancer (CC) receiving radical chemoradiotherapy (R-CT), abdominal
radical hysterectomy (ARH), or neoadjuvant chemotherapy and radical surgery
(NACT). Methods: Overall, 4086 patients in 47 hospitals from 2004 to
2018 were divided into groups according to stage (4029 with stage IIIC1 and 57
with stage IIIC2). Kaplan-Meier and Cox regression analyses were applied to
compare the 5-year overall survival (OS) and disease-free survival (DFS) of the
three initial treatments before and after propensity score matching (PSM).
Results: The 5-year DFS was worse in patients with stage IIIC2 than in
those with stage IIIC1 (post-PSM: 68.3% vs. 39.9%, p