Objective: Aim of the study was to examine the associations between severity of depression in adolescence and parent attitudes/family functioning. Methods: Thirty adolescents with depression and 30 age and gender matched controls; and their parents participated in this study. Adolescents were evaluated by ‘Disorders and Schedule for Affective Disorders and Schizophrenia for School Age Children-Present and Lifetime Version’. Perceived parent attitudes was assessed by ‘The Parental Acceptance-Rejection/Control Questionnaire’. ‘The Childhood Depression Inventory’ was administered to evaluate severity of depression in adolescents. Family functioning was assessed by ‘The Family Assessment Device’ which was filled by both parents. Results: Adolescents with depression perceived their mothers and fathers as more rejecting than did adolescents without depression. There wasn’t a significantly different between perceived parental control levels in two groups. In mother-reported family functioning scores including problem solving, communication, roles, affective, responsiveness, behavior control and general functioning in depression group were higher than those in controls. In father-reported family functioning scores including problem solving and affective involvement in depression group was higher than that in controls. Adolescents’ depression levels were positively correlated with perceived paternal rejection levels and impairment of family functioning levels. There wasn’t a significant relation between adolescents’ depression severity and perceived paternal control levels. Discussion: Our results suggest that adolescent depression was associated with both perceived maternal and paternal rejection and impairment in family functioning. Long-term follow-up studies are required to determine causal/temporal relationships between adolescent depression with parent attitudes and family functioning. [Anadolu Psikiyatri Derg 2016; 17(5.000): 403-410]