Cite this article
Volume | Year
Reviews in Cardiovascular Medicine (RCM) is published by IMR Press from Volume 19 Issue 1 (2018). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with MedReviews, LLC.
Open Access Case Review
Congenital Long QT Syndrome
1 Department of Internal Medicine, Wright State University Boonshoft School of Medicine, Section of Electrophysiology, Good Samaritan Hospital, Dayton, OH
Rev. Cardiovasc. Med. 2006, 7(3), 160–165;
Published: 30 September 2006
Long QT syndrome (LQTS) can be asymptomatic—identifiable as an incidental finding on electrocardiogram—or it can present with palpitation, syncope, seizures, or sudden cardiac death. LQTS is characterized by a prolonged QT interval, which can be associated with a specific form of polymorphic ventricular tachycardia known as torsade de pointes. Other electrocardiogram changes in LQTS include T-wave abnormalities, particularly bifid T waves, U waves, and T-wave alternans. The precipitating factors of LQTS include electrolyte abnormalities, bradyarrhythmias, medications (such as antiarrhythmic drugs, antibiotics, antipsychotics, and antihistamines), and myocardial ischemia. The authors report a case of LQTS in a 47-year-old woman with no other significant cardiac history.
Long QT syndrome
Torsade de pointes
Sudden cardiac death
Jervell and Lange-Nielsen syndrome