IMR Press / RCM / Volume 3 / Issue S5 / pii/1561516748762-1914031112

Reviews in Cardiovascular Medicine (RCM) is published by IMR Press from Volume 19 Issue 1 (2018). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by IMR Press on as a courtesy and upon agreement with MedReviews, LLC.

Open Access Review
Clinical Experience with Drug-Eluting Stents
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1 Department of Medicine, (Knight Cardiac Catheterization Laboratory, Cardiovascular Division, Massachusetts General Hospital) Harvard Medical School, Boston, MA
Rev. Cardiovasc. Med. 2002, 3(S5), 31–37;
Published: 20 November 2002
Despite dramatic improvements in catheter and stent technology, in-stent restenosis continues to hamper initial procedural success in 10% to 50% of patients undergoing coronary intervention. Recent breakthroughs in polymer science and local drug delivery have shown tremendous promise in the long-sought-after goal of delivering antirestenotic therapy directly from a stent. Clinical trials examining several novel antirestenotic agents, particularly sirolimus and paclitaxel, have shown astonishing reduction in restenosis following stenting. Through examination of the clinical experience to date, we may gain insight into the current and future utility of drug-eluting stents in our clinical practice.
Local drug delivery
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