IMR Press / RCM / Volume 15 / Issue 4 / DOI: 10.3909/ricm0720

Reviews in Cardiovascular Medicine (RCM) is published by IMR Press from Volume 19 Issue 1 (2018). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by IMR Press on as a courtesy and upon agreement with MedReviews, LLC.

Open Access Review
Renal Denervation: Current Status and Future Applications
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1 Division of Internal Medicine, Mount Sinai Heart Institute, Miami Beach, FL
2 Columbia University Division of Cardiology, Mount Sinai Heart Institute,Miami Beach, FL
Rev. Cardiovasc. Med. 2014, 15(4), 351–357;
Published: 30 December 2014
Despite the variety of antihypertensive agents that are available, resistant hypertension remains a significant clinical problem and a substantial economic burden. Over the past several years, renal sympathetic denervation has been introduced as a potential therapeutic option for this clinical problem. It is a catheter-based procedure that is showing promising results and appears to be associated with minimal or low risk. Thus far, two completed clinical trials have demonstrated excellent safety and encouraging outcomes. A review of these trials is the focus of this article, in addition to the analysis of ongoing studies, and the possible future applications of this technique.
Resistant hypertension
Renal sympathetic denervation
Sympathetic overactivity
Cardiovascular disease
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