Background and objective: Many concepts related to sexual dissatisfaction are discussed here. Two of these concepts are sexual self-confidence and sexual self-efficacy. The main aim of this research is to explore the mediation effect of sexual self-confidence on the relationship between sexual self-efficacy and sexual dissatisfaction. Methods: This research was carried out with the relational screening model. In this context, sexual self-efficacy, sexual dissatisfaction, and sexual self-confidence were examined with the Pearson correlation coefficient and mediation analysis. Results: The results of the correlation analysis demonstrated that sexual self-confidence and sexual self-efficacy are significantly related to sexual dissatisfaction. Before the mediation analysis was carried out, the sexual self-efficacy meaningfully predicts sexual dissatisfaction in the first regression model. The mediation analysis proved that sexual self-confidence has a mediation role in the relationship between sexual self-efficacy and sexual dissatisfaction. Conclusion: It is thought that sexual self-confidence is a more important factor for men’s sexual satisfaction or dissatisfaction than is sexual self-efficacy.