IMR Press / JOMH / Volume 17 / Issue 2 / DOI: 10.31083/jomh.2021.014
Open Access Editorial
The molecule that makes prostate cancer easy to find shows why it will be so difficult to cure
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1 Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada
2 Independent Scholar, Port Moody, British Columbia, Canada
*Correspondence: (Richard J. Wassersug)
These authors contributed equally.
J. Mens. Health 2021, 17(2), 1–3;
Submitted: 23 December 2021 | Accepted: 13 January 2021 | Published: 8 April 2021
Copyright: © 2021 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license (

PSA is an enzyme that helps liquefy semen after a man ejaculates. Liquifying the semen frees sperm cells so they can swim to an egg and fertilize it. PSA’s function is so essential for mammalian reproduction that prostate cancer has evolved a multitude of ways to avoid the body’s own defences against cancerous prostate cells. As a testimony to how important PSA is to reproduction, highly mutated prostate cells still produce PSA. This makes the PSA test a good clinical tool for tracking the progression of the disease. At the same time, it also is an ominous sign of how hard it will be to find a simple cure for prostate cancer.

Prostate-specific antigen
Prostate cancer
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