It has been previously established that total antioxidant capacity
concentrations of blood on the first day of ischemic stroke could predict
mortality. Therefore, our study objective was to determine whether total
antioxidant capacity concentrations in the blood during the first week of a
cerebral infarction could help predict mortality. We included severe and
malignant middle cerebral artery infarction patients (affecting 50% or more of
the territory in computed tomography and a score of nine or fewer points in the
Glasgow Coma Scale). Serum total antioxidant capacity concentrations were
determined on days first, fourth, and eighth of the diagnosis of a malignant
middle cerebral artery infarction. Higher serum total antioxidant capacity
concentrations at first (
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Mortality prediction of ischemic stroke patients without thrombectomy by blood total antioxidant capacity
Leonardo Lorente1,*, María M. Martín2, Agustín F. González-Rivero3, Antonia Pérez-Cejas4, Pedro Abreu-González5, Rafael Sabatel6, Luis Ramos-Gómez7, Mónica Argueso8, Jordi Solé-Violán9, Juan J. Cáceres10, Alejandro Jiménez11, Victor García-Marín12
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1
Intensive Care Unit, Hospital Universitario de Canarias, Ofra, s/n, La Laguna, Santa Cruz de Tenerife, 38320, Spain
2
Intensive Care Unit, Hospital Universitario Nuestra Señora de Candelaria, Crta del Rosario s/n Santa Cruz de Tenerife, 38010, Spain
3
Laboratory Department, Hospital Universitario de Canarias, Ofra, s/n, La Laguna, Santa Cruz de Tenerife, 38320, Spain
4
Laboratory Department, Hospital Universitario de Canarias, Ofra, s/n, La Laguna, Tenerife, 38320, Spain
5
Department of Phisiology, Faculty of Medicine, University of the La Laguna, La Laguna, Santa Cruz de Tenerife, 38320, Spain
6
Department of Radiology, Hospital Universitario de Canarias, Ofra, s/n, La Laguna, Santa Cruz de Tenerife, 38320, Spain
7
Intensive Care Unit, Hospital General La Palma, Buenavista de Arriba s/n, Breña Alta, La Palma, 38713, Spain
8
Intensive Care Unit, Hospital Clínico Universitario de Valencia, Avda, Blasco Ibáñez nº17-19 Valencia, 46004, Spain
9
Intensive Care Unit, Hospital Universitario Dr. Negrín. CIBERES, Barranco de la Ballena s/n Las Palmas de Gran Canaria, 35010, Spain
10
Intensive Care Unit, Hospital Insular, Plaza Dr. Pasteur s/n, Las Palmas de Gran Canaria, 35016, Spain
11
Research Unit, Hospital Universitario de Canarias, Ofra, s/n. La Laguna, Santa Cruz de Tenerife, 38320, Spain
12
Department of Neurosurgery, Hospital Universitario de Canarias, Ofra, s/n, La Laguna, Santa Cruz de Tenerife, 38320, Spain
*Correspondence: lorentemartin@msn.com (Leonardo Lorente)
J. Integr. Neurosci. 2020, 19(3), 501–506;
https://doi.org/10.31083/j.jin.2020.03.101
Submitted: 10 April 2020 | Revised: 16 July 2020 | Accepted: 20 July 2020 | Published: 30 September 2020
Copyright: © 2020 Lorente et al. Published by IMR Press.
This is an open access article under the CC BY 4.0 license (https://creativecommons.org/licenses/by/4.0/).
Abstract
Keywords
Total antioxidant capacity
prognosis
ischemic stroke
blood-brain barrier
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Fig. 1.