A macro-quantum model is developed to describe spontaneous processes in terms of computable equations. The resultant macro-quantum wave equation (Schrödinger-type equation) is solved via a Madelung transformation to yield a complex-valued solution whose real part gives the macro-quantum potential energy. We show that the mechanism responsible for spontaneous phase differences is a pilot-wave force attributed to the internal thermo-quantum energy. Its functionality contributes to the phase synchrony in the emergence of ‘long-range order’ occurring by means of the actualized phase differences of the spontaneous processes. Macroscopic pilot-wave theory is used to describe how informational patterns carry ‘meaning’ via a ‘consciousness code’ arising from thermo-quantum fluctuations. The resultant negentropic entanglement of the actualized phase differences according to panexperientialism acts as a ‘conscious pilot’ that provides stability through a pilot-wave guided negentropic action emerging from macro-quantum potential energy. In view of the above, the thermo-quantum consciousness is a process based on Aristotelian doctrine of causes. The material cause as uncertainty in the brain expressed through the wave function, naturally leads to pilot-wave guided negentropic action as the efficient cause of conscious recall that actualizes spontaneous potentiality as its formative cause, with inner experiences as the final cause. It is the final cause that is expressed in memory after consciousness and their interrelationship with uncertainty in the brain, that forms a relational holon.