IMR Press / JIN / Volume 17 / Issue 2 / DOI: 10.31083/JIN-170045
Open Access Research article
Transcranial direct current stimulation based on qEEG combining positive psychotherapy for major depression
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1 Educational Sciences & Psychology Department, University of Isfahan, Isfahan, Iran
2 Department of Health and Work Science, University of G$\ddot{a}$vle, G$\ddot{a}$vle, Sweden
3 Department of Psychology, Cognitive Division, Lund University, Sweden
4 University of Tabriz, Tabriz, Iran
*Correspondence: (Zahra Khayyer)
J. Integr. Neurosci. 2018, 17(2), 89–96;
Submitted: 21 April 2017 | Accepted: 10 August 2017 | Published: 15 May 2018

Frontal cortex activity is reduced in the left hemisphere during depression. Transcranial direct current stimulation is a non-invasive neuromodulation technique that can increase frontal cortex activity. Therapy based on transcranial Direct Current Stimulation and positive psychology therapy was applied for improving patients' quality of life. The present study compared three conditions of subjects with clinical depression; (a) transcranial Direct Current Stimulation therapy, (b) positive psychotherapy, and (c) combined treatment. Hamilton Depression Rating Scale, Adult State Hope Scale and Optimism/Pessimism Scale was used at baseline, 2-week, 4-week, and 3-month follow-up. Combined condition participants showed greater reduction in depressed mood, improved hope and optimism after 4-week as well as during 3-month follow-up than the other conditions. Results are discussed in terms of additive or synergistic relation between transcranial direct current stimulation and positive psychology treatment.

Frontal cortex activity
case study
major depression
transcranial direct current stimulation
quantitative electroencephalogram
positive psychotherapy
Fig. 1.
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