Frontiers in Bioscience-Scholar (FBS) is published by IMR Press from Volume 13 Issue 1 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Volume 4 Issue 2 2012

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Open Access Article

The role of tumor-associated macrophage in tumor progression

Koji Fukuda, Aya Kobayashi, Kounosuke Watabe

Front. Biosci. (Schol Ed) 2012, 4(2), 787–798; https://doi.org/10.2741/S299

(This article belongs to the Special Issue Pathogenesis of tumor progression in breast and prostate cancer)

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15

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Open Access Article

Pathologic effects of RNase-L dysregulation in immunity and proliferative control

Heather J. Ezelle, Bret A. Hassel

Front. Biosci. (Schol Ed) 2012, 4(2), 767–786; https://doi.org/10.2741/S298

(This article belongs to the Special Issue RNA binding proteins in disease)

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6

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11

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Open Access Article

TGF-beta antiproliferative effects in tumor suppression

Stephan Christopher Jahn, Mary Elizabeth Law, Patrick Evan Corsino, Brian Keith Law

Front. Biosci. (Schol Ed) 2012, 4(2), 749–766; https://doi.org/10.2741/S297

(This article belongs to the Special Issue TGF-beta signaling and cancer)

Abstract PDF(326.07KB)

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3

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24

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Open Access Article

Sulphur-containing non enzymatic antioxidants: therapeutic tools against cancer

Jose M. Mates, Juan A. Segura, Francisco J. Alonso, Javier Marquez

Front. Biosci. (Schol Ed) 2012, 4(2), 722–748; https://doi.org/10.2741/S296

(This article belongs to the Special Issue Novel strategies for detection, prevention and treatment of cancer)

Abstract PDF(373.34KB)

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27

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47

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Open Access Article

The multiple roles of tissue factor in wound healing

Maureane Hoffman, Dougald M. Monroe

Front. Biosci. (Schol Ed) 2012, 4(2), 713–721; https://doi.org/10.2741/S295

(This article belongs to the Special Issue Factor VIIa, tissue factor, and tissue factor pathway inhibitor: roles in hemostasis, thrombosis and beyond)

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6

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10

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Open Access Article

Deciphering the role of Toll-like receptors in humoral responses to Borreliae

Gregory S. Dickinson, Kishore R. Alugupalli

Front. Biosci. (Schol Ed) 2012, 4(2), 699–712; https://doi.org/10.2741/S294

(This article belongs to the Special Issue Exploiting toll-like receptors to interfere with the B cell response)

Abstract PDF(308.86KB)

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1

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13

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Open Access Article

Innate and adaptive immunity in host-microbiota mutualism

Andrew J. Macpherson, Markus B. Geuking, Kathy D. McCoy

Front. Biosci. (Schol Ed) 2012, 4(2), 685–698; https://doi.org/10.2741/S293

(This article belongs to the Special Issue Inflammatory bowel disease -1)

Abstract PDF(251.95KB)

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3

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15

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Open Access Article

EGF-receptor signaling and epithelial-mesenchymal transition in human carcinomas

Ala-Eddin Al Moustafa, Amal Achkhar, Amber Yasmeen

Front. Biosci. (Schol Ed) 2012, 4(2), 671–684; https://doi.org/10.2741/S292

(This article belongs to the Special Issue E-cadherin function in development and cancer)

Abstract PDF(760.99KB)

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55

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55

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Open Access Article

Nox enzymes and oxidative stress in atherosclerosis

Adrian Manea, Maya Simionescu

Front. Biosci. (Schol Ed) 2012, 4(2), 651–670; https://doi.org/10.2741/S291

(This article belongs to the Special Issue Cellular and molecular mechanisms of cardiovascular diseases: role of oxidative stress)

Abstract PDF(409.41KB)

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10

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26

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Open Access Article

14-3-3zeta cooperates with phosphorylated Plk1 and is required for correct cytokinesis

Jian Du, Lijian Chen, Xin Luo, Yuxian Shen, ... Xuebiao Yao

Front. Biosci. (Schol Ed) 2012, 4(2), 639–650; https://doi.org/10.2741/S290

(This article belongs to the Special Issue Biosensors and their applications)

Abstract PDF(1.86MB)

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7

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18

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Open Access Article

Inflammation and thrombosis: new insights

Patrick A. Lester, Jose A. Diaz, Katherine A. Shuster, Peter K. Henke, ... Daniel D. Myers

Front. Biosci. (Schol Ed) 2012, 4(2), 620–638; https://doi.org/10.2741/S289

(This article belongs to the Special Issue Blood coagulation, inflammation, and thrombosis)

Abstract PDF(679.87KB)

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3

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17

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Open Access Article

Optimizing stem cell collection through CXCR4 antagonists

Hemchandra Mahaseth, Jonathan Kaufman

Front. Biosci. (Schol Ed) 2012, 4(2), 611–619; https://doi.org/10.2741/S288

(This article belongs to the Special Issue New insights in immunology)

Abstract PDF(183.41KB)

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17

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Open Access Review

Stroke, angiogenesis and phytochemicals

Yu-Chang Chen, Jui-Sheng Wu, Shun-Tai Yang, Chien-Yu Huang, ... Teng-Nan Lin

Front. Biosci. (Schol Ed) 2012, 4(2), 599–610; https://doi.org/10.2741/S287

(This article belongs to the Special Issue Oxidative stress and neurodegenerative disorders: protective effects of natural products)

Abstract PDF(552.15KB)

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10

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48

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Open Access Review

Molecular mechanisms of the neuroprotective/neurorescue action of multi-target green tea polyphenols

Silvia A. Mandel, Orly Weinreb, Tamar Amit, Moussa B.H. Youdim

Front. Biosci. (Schol Ed) 2012, 4(2), 581–598; https://doi.org/10.2741/S286

(This article belongs to the Special Issue Oxidative stress and neurodegenerative disorders: protective effects of natural products)

Abstract PDF(462.55KB)

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29

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24

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Open Access Review

Myocardial substrate metabolism in heart disease

Rhys D. Evans, Kieran Clarke

Front. Biosci. (Schol Ed) 2012, 4(2), 556–580; https://doi.org/10.2741/s285

(This article belongs to the Special Issue Cardiac remodelling in uraemic heart disease)

Abstract PDF(345.05KB)

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12

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19

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Open Access Review

Endosomal trafficking in animal cytokinesis

Conor P. Horgan, Mary W. McCaffrey

Front. Biosci. (Schol Ed) 2012, 4(2), 547–555; https://doi.org/10.2741/s284

(This article belongs to the Special Issue Membrane trafficking and disease)

Abstract PDF(264.17KB)

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15

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12

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Open Access Review

Regulation of cardiac excitability by protein kinase C isozymes

Julio Cesar Batista Ferreira, Daria Mochly-Rosen, Mohamed Boutjdir

Front. Biosci. (Schol Ed) 2012, 4(2), 532–546; https://doi.org/10.2741/s283

(This article belongs to the Special Issue Membrane to myofilament: calcium regulation and the progression to congestive heart failure)

Abstract PDF(527.57KB)

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21

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8

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Open Access Review

CARs: Driving T-cell specificity to enhance anti-tumor immunity

Partow Kebriaei, Susan S. Kelly, Pallavi Manuri, Bipulendu Jena, ... Laurence J. N. Cooper

Front. Biosci. (Schol Ed) 2012, 4(2), 520–531; https://doi.org/10.2741/s282

(This article belongs to the Special Issue New insights in immunology)

Abstract PDF(593.14KB)

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5

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5

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Open Access Review

Tumor gangliosides and T cells: A deadly encounter

Dewan Md Sakib Hossain, Suchismita Mohanty, Pallab Ray, Tanya Das, Gaurisankar Sa

Front. Biosci. (Schol Ed) 2012, 4(2), 502–519; https://doi.org/10.2741/s281

(This article belongs to the Special Issue Glycobiology of cancer)

Abstract PDF(829.90KB)

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10

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14

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Open Access Review

The contrasting oncogenic and tumor suppressor roles of FES

Peter A. Greer, Shigeru Kanda, Thomas E. Smithgall

Front. Biosci. (Schol Ed) 2012, 4(2), 489–501; https://doi.org/10.2741/s280

Abstract PDF(709.98KB)

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6

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9

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Open Access Review

Histamine receptor subtypes: a century of rational drug design

Miriam Walter, Holger Stark

Front. Biosci. (Schol Ed) 2012, 4(2), 461–488; https://doi.org/10.2741/s279

(This article belongs to the Special Issue Histamine revisited: the H4 receptor in health and disease)

Abstract PDF(625.31KB)

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47

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16

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Open Access Review

Suppression of autophagy by BCR/ABL

Bruno Calabretta, Paolo Salomoni

Front. Biosci. (Schol Ed) 2012, 4(2), 453–460; https://doi.org/10.2741/s278

(This article belongs to the Special Issue Tumor suppressors and stress signaling in cancer)

Abstract PDF(401.45KB)

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7

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29

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Open Access Review

Staufen: from embryo polarity to cellular stress and neurodegeneration

Leandro Julian Martinez Tosar, Maria Gabriela Thomas, Maria Veronica Baez, Irene Ibanez, ... Graciela Lidia Boccaccio

Front. Biosci. (Schol Ed) 2012, 4(2), 432–452; https://doi.org/10.2741/s277

(This article belongs to the Special Issue RNA binding proteins in disease)

Abstract PDF(467.22KB)

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9

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22

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Open Access Review

Targeting endoplasmic reticulum stress for cancer therapy

Axel H. Schonthal

Front. Biosci. (Schol Ed) 2012, 4(2), 412–431; https://doi.org/10.2741/s276

(This article belongs to the Special Issue Novel strategies for detection, prevention and treatment of cancer)

Abstract PDF(850.14KB)

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57

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12

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Open Access Review

Oxidative stress induced cellular signaling in RPE cells

Alexa Klettner

Front. Biosci. (Schol Ed) 2012, 4(2), 392–411; https://doi.org/10.2741/s275

(This article belongs to the Special Issue Pathogenetic mechanism of age-related macular degeneration)

Abstract PDF(633.16KB)

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46

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