IMR Press / FBS / Volume 3 / Issue 2 / DOI: 10.2741/S173

Frontiers in Bioscience-Scholar (FBS) is published by IMR Press from Volume 13 Issue 1 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with Frontiers in Bioscience.

Obesity and prostate cancer: collateral damage in the battle of the bulge
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1 Division of Urologic Surgery, Department of Surgery and the Duke Prostate Center, Duke University School of Medicine, Durham, NC
2 Department of Surgery, Veterans Administration Medical Center Durham, Durham, NC
3 Department of Pathology, Duke University School of Medicine, Durham, NC

*Author to whom correspondence should be addressed.

Academic Editor: Jiezhong Chen

Front. Biosci. (Schol Ed) 2011, 3(2), 594–605;
Published: 1 January 2011
(This article belongs to the Special Issue Obesity and cancer)

Prostate cancer is the most common non-cutaneous malignancy diagnosed in US men. With the increasing prevalence of obesity, it is of interest how this condition impacts prostate cancer. However, only recently has the relationship between obesity and prostate cancer been earnestly studied by investigators. Indeed, the relationship between obesity and prostate cancer appears to be complex one. Therefore, we sought to review the most recent and relevant epidemiological data discussing the link between prostate cancer and obesity. In this review, we will discuss both "biological" and "non-biological" means by which obesity may potentially impact prostate cancer.

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