IMR Press / FBL / Volume 9 / Issue 5 / DOI: 10.2741/1451

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Article
Can ends justify the means? Digging deep for human fusion genes of prokaryotic origin
Show Less
1 School of Mechanical and Production Engineering, Nanyang Center for Supercomputing and Visualization, Nanyang Technological University, Singapore 639798
Front. Biosci. (Landmark Ed) 2004, 9(5), 2964–2971; https://doi.org/10.2741/1451
Published: 1 September 2004
Abstract

Gene fusion has been described as an important evolutionary phenomenon. This report focuses on identifying, analyzing, and tabulating human fusion proteins of prokaryotic origin. These fusion proteins are found to mimic operons, simulate protein-protein interfaces in prokaryotes, exhibiting multiple functions and alternative splicing in humans. The accredited biological functions for each of these proteins is made available as a database at http://sege.ntu.edu.sg/wester/fusion/

Share
Back to top