IMR Press / FBL / Volume 7 / Issue 4 / DOI: 10.2741/A858

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Article
The glycobiology of implantation
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1 Department of Biological Sciences, University of Delaware, Newark, DE 19707, USA
Academic Editor:William Okulicz
Front. Biosci. (Landmark Ed) 2002, 7(4), 1535–1544; https://doi.org/10.2741/A858
Published: 1 June 2002
(This article belongs to the Special Issue Progesterone action and the endometrium)
Abstract

Embryo implantation involves complex, coordinated interactions of cell surface components of embryonic (trophectoderm/trophoblast) and uterine cells. Oligosaccharides are common constituents of cell surface molecules. A variety of oligosaccharide structures have been identified at embryonic and uterine cell surfaces and change dynamically during progression of the implantation reaction. In many cases, the oligosaccharides have been shown to have biological activities with great relevance to the implantation process. This review summarizes the available information on glycoconjugates as it relates to the implantation process. It is suggested that carbohydrate bearing molecules at embryonic and uterine cell surfaces play diverse roles during the implantation process that are similar to the roles suggested for these molecules in other biological contexts.

Keywords
Glycobiology
Implantation
Mucins
Proteoglycans
Uterus
Review
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