IMR Press / FBL / Volume 6 / Issue 3 / DOI: 10.2741/Fowler

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Article

Polymorphism of the human MUC genes

Show Less
1 Galton Laboratory, Department of Biology, Wolfson House, 4 Stephenson Way, London NW1 2HE

Academic Editor: Surinder Batra

Front. Biosci. (Landmark Ed) 2001, 6(3), 1207–1215; https://doi.org/10.2741/Fowler
Published: 1 October 2001
(This article belongs to the Special Issue Mucins)
Abstract

Mucins encoded by the MUC genes share the common feature of having an extensive tandem repeat region that encompasses a large proportion of the coding sequence. In many of the genes this tandem repeat region shows a great deal of allelic length variation and recently studies have demonstrated person to person variation in pattern of nucleotide or amino-acid changes in the repeat units. The length and sequence variability will be discussed in this review, as will its role in disease susceptibility.

Share
Back to top