IMR Press / FBL / Volume 5 / Issue 5 / DOI: 10.2741/rudolf

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with Frontiers in Bioscience.

Apoptosis - when the cells begin to dance
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1 Department of Medical Biology and Genetics, Charles University Faculty of Medicine in Hradec Kralove, Simkova 870, 500 01 Hradec Kralove I, Czech Republic
Front. Biosci. (Landmark Ed) 2000, 5(5), 1–2;
Published: 1 September 2000

We present a 24-hour time-lapse videosequence of in vitro behavior of Hep-2 cells treated with 10 µg/ml Etoposide, a topoisomerase II inhibitor. The cell behavior was recorded by a Mitsubishi video recorder, HS-S5600. In the presented sequence, we show the typical cell rounding accompanied by formation of numerous pseudopodia and rapid rhythmical contractions, so called membrane blebbing known as "dance of death".

In vitro
Time-lapse Videomicroscopy
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