IMR Press / FBL / Volume 5 / Issue 3 / DOI: 10.2741/trudel

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Article
Progress in molecular genetics of autosomal dominant polycystic kidney disease
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1 Institut de Recherches Cliniques de Montreal, Molecular Genetics and Development, Faculte de Medecine de l'Universite de Montreal, Montreal, Quebec H2W 1R7, Canada
Front. Biosci. (Landmark Ed) 2000, 5(3), 312–320; https://doi.org/10.2741/trudel
Published: 1 March 2000
Abstract

Among the prevalent human genetic disorders, human autosomal dominant polycystic kidney disease is certainly one of the most challenging, both from a clinical and a fundamental perspective. In the recent years, important progress opened novel research avenues to elucidate the genetic basis, the cellular pathophysiologic mechanisms and the molecular function of genes and proteins involved in autosomal dominant polycystic kidney disease.

Keywords
Polycystic kidney disease
Kidney
Epithelium
Renal development
Pkd1
Pkd2
Review
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