IMR Press / FBL / Volume 3 / Issue 4 / DOI: 10.2741/A343

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with Frontiers in Bioscience.

The role of carbohydrates in mammalian sperm-egg interactions: how important are carbohydrate epitopes?
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1 Division of Research, Department of Obstetrics and Gynecology, Medical College of Ohio, Richard d. Ruppert Health Center, 3120 Glendale Avenue, Toledo, OH 43614-5809, USA
Front. Biosci. (Landmark Ed) 1998, 3(4), 1028–1038;
Published: 1 October 1998

Evidence implicating the involvement of carbohydrates in fertilization has been reported for decades in species which span the phylogenetic scale. The exact nature and role of these ligands in fertilization, however, has eluded investigators. Here, such investigations are reviewed as they relate to mammalian fertilization, with the principle focus on reviewing the role of carbohydrates involved in the primary binding event between sperm cell and egg.

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