IMR Press / FBL / Volume 26 / Issue 11 / DOI: 10.52586/5012
Open Access Article
The global, regional, and national burden of laryngeal cancer and the attributable risk factors in all countries and territories during 2007–2017
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1 Department of Otorhinolaryngology and Head and Neck Surgery, The Affiliated Lihuili Hospital, Ningbo University, 315040 Ningbo, Zhejiang, China
2 Department of Biochemistry and Molecular Biology, Ningbo University School of Medical, 315211 Ningbo, Zhejiang, China
3 Department of Global Health, Hwa Mei Hospital, University of Chinese Academy of Sciences, 315010 Ningbo, Zhejiang, China
4 Department of Global Health, Ningbo Institute of Life and Health Industry, University of Chinese Academy of Sciences, 315010 Ningbo, Zhejiang, China
Front. Biosci. (Landmark Ed) 2021, 26(11), 1097–1105; https://doi.org/10.52586/5012
Submitted: 3 April 2021 | Revised: 26 April 2021 | Accepted: 24 June 2021 | Published: 30 November 2021
Copyright: © 2021 The Author(s). Published by BRI.
This is an open access article under the CC BY 4.0 license (https://creativecommons.org/licenses/by/4.0/).
Abstract

Background: Data for the global burden of laryngeal cancer (LC) are limited. Methods: We reported the incidence of, disability-adjusted life years (DALYs), and deaths due to LC by age, sex and by social-demographic index (SDI) in all countries and territories during 2007 to 2017, based on data from the Global Burden of Disease (GBD) 2017 study. We also assessed the risk factors for LC-associated DALYs and deaths through a comparative risk assessment framework. Results: Globally, from 2007 to 2017, the age-standardized incidence rate increased by 0.95%, the age-standardized DALY rate decreased by 8.75%, and the age-standardized death rate decreased by 7.66%. The age-standardized incidence, DALY, and death rates in 2017 were all the highest in the low SDI quintile. The middle SDI quintile witnessed the highest percentage changes in age-standardized incidence, DALY, and death rates during 2007–2017. At the GBD regional level, the highest age-standardized incidence, DALY, and death rates in 2017 occurred in the Caribbean, followed by South Asia. East Asia showed the largest increases in age-standardized incidence, DALY, and death rates from 2007 to 2017. At the national level, China and Jamaica reported the largest percentage increases in the age-standardized incidence, DALY, and death rates over the study period. Conclusion: The global age-standardized incidence of LC remain stable. However, the age-standardized DALY and death rates decreased significantly over the study period. Impact: Our findings will be beneficial for developing policies to reduce the disease burden of LC in particular regions or countries.

Keywords
Burden of disease
Laryngeal cancer
Incidence
Disability-adjusted life years (DALYs)
Death
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