IMR Press / FBL / Volume 26 / Issue 10 / DOI: 10.52586/4995
Open Access Review
Sarcopenia and perioperative management of elderly surgical patients
Show Less
1 Department of Anesthesiology and Perioperative Medicine, The First Affiliated Hospital of Nanjing Medical University, 210029 Nanjing, Jiangsu, China
2 Department of Anesthesiology, Affiliated Stomatological Hospital, Nanjing Medical University, 210029 Nanjing, Jiangsu, China
3 Department of Cardiology, The Third Affiliated Hospital of Soochow University, 212003 Changzhou, Jiangsu, China
*Correspondence: (Chun Yang); (Cunming Liu)
These authors contributed equally.
Front. Biosci. (Landmark Ed) 2021, 26(10), 882–894;
Submitted: 18 July 2021 | Revised: 12 September 2021 | Accepted: 16 September 2021 | Published: 30 October 2021
Copyright: © 2021 The Author(s). Published by BRI.
This is an open access article under the CC BY 4.0 license (

Sarcopenia is the age-related loss of skeletal muscle mass, accompanied by reduced muscle strength or physical function. As the global population continues to age, the prevalence of sarcopenia is gradually increasing. It is conceivable that an increasing number of patients with sarcopenia will be scheduled for surgery and anesthesia in the near future. The complex pathogenesis and clinical features of sarcopenia have brought huge challenges to perioperative management, especially in clinical anesthesia. However, there are currently neither guidelines nor expert consensus on the perioperative management of patients with sarcopenia. In this review, we summarize and elaborate on the pathogenesis, diagnosis, and perioperative precautions of sarcopenia, thereby providing information on the perioperative and anesthestic management of patients with sarcopenia.

Anesthetic management
Fig. 1.
Back to top