IMR Press / FBL / Volume 26 / Issue 10 / DOI: 10.52586/4982
Open Access Original Research
Clinical features of pneumonia in severely malnourished children with diarrhoea compared to those without diarrhoea
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1 Department of Pharmacy, East West University, 1212 Dhaka, Bangladesh
2 Department of Anesthesia, Pain Management and Perioperative Medicine, Faculty of Medicine, Dalhousie University, Halifax, NS B3H 1X5, Canada
3 Nutrition & Clinical Services Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), 1212 Dhaka, Bangladesh
*Correspondence: (Sufia Islam)
Front. Biosci. (Landmark Ed) 2021, 26(10), 717–722;
Submitted: 22 June 2021 | Revised: 27 July 2021 | Accepted: 5 August 2021 | Published: 30 October 2021
Copyright: © 2021 The Author(s). Published by BRI.
This is an open access article under the CC BY 4.0 license (

Introduction: Pneumonia and diarrhoea are amongst the most common causes for hospital admission for children in low- and middle-income countries such as Bangladesh. Undernourished children often have more severe infections and a higher morbidity and mortality. Objective: The objective of this study was to determine the clinical features and outcomes of pneumonia in severely malnourished children with and without diarrhoea. Methodology: A retrospective chart analysis was carried out on children under 5 years of age who were admitted in intensive care unit of the Dhaka hospital of International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b). A total of 245 severe acute malnourished children with pneumonia and diarrhoea (PD group) were compared with 89 children with pneumonia only (PO group). Results: A significantly higher number of children from the PD group had some/severe dehydration (16.3% vs. 1.1%; p < 0.005) when compared with children from the PO group. The PD group showed less cough (83.3% vs. 100%; p < 0.001), lower chest wall indrawing (40.4% vs. 60.7%; p = 0.001), and crackles (62.4% vs. 87.6%; p < 0.001) compared to the PO group at the time of admission. Conclusion: Early diagnosis and treatment of some/severe dehydration in addition to WHO recommended other routine treatment of diarrhoea, pneumonia and severe acute malnutrition in children may help to reduce childhood morbidity and mortality especially in low- and middle-income countries.

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