IMR Press / FBL / Volume 25 / Issue 10 / DOI: 10.2741/4882

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with Frontiers in Bioscience.

Japanese encephalitis virus: a review on emerging diagnostic techniques
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1 DBT-National Institute of Animal Biotechnology (DBT-NIAB), Hyderabad-500032, Telangana, India
Send correspondence to: Sonu Gandhi, DBT-National Institute of Animal Biotechnology (DBT-NIAB), Hyderabad-500032, Telangana, India, Tel: 040-23120127, Fax: 040-23120130, E-mail:
Front. Biosci. (Landmark Ed) 2020, 25(10), 1875–1893;
Published: 1 June 2020

Japanese Encephalitis Virus (JEV) is the most common Flavivirus based mosquito borne viral encephalitis in the world, especially in countries of South-East Asia. The conventional methods such as Enzyme-Linked Immunosorbent Assays (ELISA), Reverse Transcriptase Polymerase Chain Reaction (RT-PCR), Plaque Reduction Neutralization Test and virus isolation are still in use today but new advances are being made to develop more efficient, inexpensive, quicker, sensitive and time-saving techniques to detect JEV. Some of these include the use of immunosensors, both lateral flow based assays and electrochemical, as well as the incorporation of nanotechnology into biosensors to develop highly sensitive detection tools. This review focuses on the recent advances that have been made to diagnose Japanese Encephalitis Virus which are critical in breaking the link to zoonotic transmission into the human population where humans are dead-end hosts.

Japanese Encephalitis Virus
Point of Care
Figure 1
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