IMR Press / FBL / Volume 23 / Issue 1 / DOI: 10.2741/4580

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with Frontiers in Bioscience.


RecA: a universal drug target in pathogenic bacteria

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1 Department of computer science and biomedical informatics, University of Thessaly, Papasiopoulou 2–4, Lamia 35100, Greece
Front. Biosci. (Landmark Ed) 2018, 23(1), 36–42;
Published: 1 January 2018
(This article belongs to the Special Issue Electrophysiology from bench to bedside)

The spread of bacterial infectious diseases due to the development of resistance to antibiotic drugs in pathogenic bacteria is an emerging global concern. Therefore, the efficacious management and prevention of bacterial infections are major public health challenges. RecA is a pleiotropic recombinase protein that has been demonstrated to be implicated strongly in the bacterial drug resistance, survival and pathogenicity. In this minireview, RecA’s role in the development of antibiotic resistance and its potential as an antimicrobial drug target are discussed.

Bacterial Infections
Antibiotic Resistance
Drug Targets
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