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Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.
Volume 17 Issue 4 2012
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- ArticleSNCG gene silencing in gallbladder cancer cells inhibits key tumorigenic activitiesShenghua Han, Feifei She, Dong Wang, Xiangqing Yao, ... Yanling ChenFront. Biosci. (Landmark Ed) 2012, 17(4), 1589–1598; https://doi.org/10.2741/4005(This article belongs to the Special Issue Pathogenesis and diagnostic modalities in cancer)16Downloads7Citations47Views
- ArticleImmunogenic epitopes of Hantaviruses' N protein are restricted to conserved regionsMauricio Menegatti Rigo, Dinler Amaral Antunes, Samuel Paulo Cibulski, Marialva Sinigaglia, ... Gustavo Fioravanti VieiraFront. Biosci. (Landmark Ed) 2012, 17(4), 1582–1588; https://doi.org/10.2741/4004(This article belongs to the Special Issue Gene networks, genome instability and evolutionary dynamics of cancer)15Downloads2Citations49Views
- ArticleThe osteon: the micromechanical unit of compact boneMaria-Grazia Ascenzi, Allison K RoeFront. Biosci. (Landmark Ed) 2012, 17(4), 1551–1581; https://doi.org/10.2741/4003(This article belongs to the Special Issue The biomineralization process: mechanism, problems, perspectives)183Downloads38Citations264Views
- Article
Cardiac tissue engineering: current state and perspectives
Loraine L Y Chiu, Rohin K Iyer, Lewis A Reis, Sara S Nunes, Milica RadisicFront. Biosci. (Landmark Ed) 2012, 17(4), 1533–1550; https://doi.org/10.2741/4002(This article belongs to the Special Issue Extracellular matrix and fibrotic diseases)62Downloads37Citations163Views - ArticleUpdate on the epidermal differentiation complexJulie Henry, Eve Toulza, Chiung-Yueh Hsu, Laurence Pellerin, ... Michel SimonFront. Biosci. (Landmark Ed) 2012, 17(4), 1517–1532; https://doi.org/10.2741/4001(This article belongs to the Special Issue Skin barrier)211Downloads107Citations458Views
- ArticleDifferential impact of Toll-like receptor signaling on distinct B cell subpopulationsAlmut Meyer-Bahlburg, David J RawlingsFront. Biosci. (Landmark Ed) 2012, 17(4), 1499–1516; https://doi.org/10.2741/4000(This article belongs to the Special Issue Exploiting toll-like receptors to interfere with the B cell response)17Downloads25Citations36Views
- ArticleRegulation of the Wip1 phosphatase and its effects on the stress responseJulie Lowe, Hyukjin Cha, Mi-Ok Lee, Sharlyn J Mazur, ... Albert J Fornace JrFront. Biosci. (Landmark Ed) 2012, 17(4), 1480–1498; https://doi.org/10.2741/3999(This article belongs to the Special Issue Tumor suppressors and stress signaling in cancer)45Downloads76Citations187Views
- ArticleGenomic instability of surgical sample and cancer-initiating cell lines from human glioblastomaArantxa Perez-Garcia, Josefa Carrion-Navarro, Minerva Bosch-Fortea, Elisa Lazaro-Ibanez, ... Angel Ayuso-SacidoFront. Biosci. (Landmark Ed) 2012, 17(4), 1469–1479; https://doi.org/10.2741/3998(This article belongs to the Special Issue Initiation of DNA replication)25Downloads10Citations46Views
- ArticleAnti-apoptotic effects of melatonin in retinal pigment epithelial cellsYang Fu, Min Tang, Ying Fan, Haidong Zou, ... Xun XuFront. Biosci. (Landmark Ed) 2012, 17(4), 1461–1468; https://doi.org/10.2741/3997(This article belongs to the Special Issue Immunoregulation and inflammatory disease)18Downloads15Citations40Views
- ArticleThe natural history of ubiquitin and ubiquitin-related domainsAlexander Maxwell Burroughs, Lakshminarayan M Iyer, L. AravindFront. Biosci. (Landmark Ed) 2012, 17(4), 1433–1460; https://doi.org/10.2741/3996(This article belongs to the Special Issue Ubiquitin-like proteins)60Downloads39Citations92Views
- ArticleMolecular mechanisms of natural killer cell regulationCarsten Watzl, Doris UrlaubFront. Biosci. (Landmark Ed) 2012, 17(4), 1418–1432; https://doi.org/10.2741/3995(This article belongs to the Special Issue Systems immunology)44Downloads12Citations250Views
- ArticleDiverse functions of nuclear non-coding RNAs in eukaryotic gene expressionMadoka Chinen, Tokio TaniFront. Biosci. (Landmark Ed) 2012, 17(4), 1402–1417; https://doi.org/10.2741/3994(This article belongs to the Special Issue Regulatory long non-coding RNA)10Downloads10Citations26Views
- ArticleDeer antler innervation and regenerationManuel Nieto-Diaz, Daniel Wolfgang Pita-Thomas, Teresa Munoz-Galdeano, Cayetana Martinez-Maza, ... Rodrigo Martinez-MazaFront. Biosci. (Landmark Ed) 2012, 17(4), 1389–1401; https://doi.org/10.2741/3993(This article belongs to the Special Issue Deer antler: a unique model for full mammalian organ regeneration)107Downloads21Citations212Views
- ArticleDNA repair mechanisms protect our genome from carcinogenesisMaria Carolina Strano Moraes, Januario Bispo Cabral Neto, Carlos Frederico Martins MenckFront. Biosci. (Landmark Ed) 2012, 17(4), 1362–1388; https://doi.org/10.2741/3992(This article belongs to the Special Issue Endogenous anticancer mechanisms)40Downloads44Citations70Views
- ArticleLINEs, SINEs and other retroelements: do birds of a feather flock together?Astrid M Roy-EngelFront. Biosci. (Landmark Ed) 2012, 17(4), 1345–1361; https://doi.org/10.2741/3991(This article belongs to the Special Issue Mobile DNAs in mammalian genomes)25Downloads38Citations99Views
- ArticleExpressing genes do not forget their LINEs: transposable elements and gene expressionKristine J Kines, Victoria P BelancioFront. Biosci. (Landmark Ed) 2012, 17(4), 1329–1344; https://doi.org/10.2741/3990(This article belongs to the Special Issue Mobile DNAs in mammalian genomes)14Downloads30Citations21Views
- ArticleMesenchymal stem cells enhance the differentiation of c-kit+ cardiac stem cellsQing Cao, Fei Wang, Jixian Lin, Qin Xu, Shuyan ChenFront. Biosci. (Landmark Ed) 2012, 17(4), 1323–1328; https://doi.org/10.2741/3989(This article belongs to the Special Issue Frontiers in in molecular cardiology and myocardial tissue engineering)6Downloads1Citations12Views
- ArticleGating and permeation of Orai channelsIsabella Derler, Rainer Schindl, Reinhard Fritsch, Christoph RomaninFront. Biosci. (Landmark Ed) 2012, 17(4), 1304–1322; https://doi.org/10.2741/3988(This article belongs to the Special Issue STIM orai calcium channels mechanisms of regulation and role in human disease)9Downloads19Citations21Views
- ArticleLPS-pretreated bone marrow stem cells as potential treatment for myocardial infractionHaiwen Zhen, Jun Wang, Lei Xue, Jun Rui, ... Yijiang ChenFront. Biosci. (Landmark Ed) 2012, 17(4), 1294–1303; https://doi.org/10.2741/3987(This article belongs to the Special Issue Frontiers in in molecular cardiology and myocardial tissue engineering)14Downloads6Citations38Views
- ArticleAlterations in the Smad pathway in human cancersDebangshu Samanta, Pran K DattaFront. Biosci. (Landmark Ed) 2012, 17(4), 1281–1293; https://doi.org/10.2741/3986(This article belongs to the Special Issue TGF-beta signaling and cancer)30Downloads61Citations322Views
- ArticleThe eggshell: structure, composition and mineralizationMaxwell T Hincke, Yves Nys, Joel Gautron, Karlheinz Mann, ... Marc D McKeeFront. Biosci. (Landmark Ed) 2012, 17(4), 1266–1280; https://doi.org/10.2741/3985(This article belongs to the Special Issue The biomineralization process: mechanism, problems, perspectives)808Downloads281Citations1502Views
- ArticleGenetics of isolated auditory neuropathiesFrancisco J Del Castillo, Ignacio Del CastilloFront. Biosci. (Landmark Ed) 2012, 17(4), 1251–1265; https://doi.org/10.2741/3984(This article belongs to the Special Issue Molecular genetics of sensorineural hearing loss)38Downloads22Citations110Views
- ArticleStat5 assumes distinct functions in mammary gland development and mammary tumor formationVida Vafaizadeh, Petra Ab Klemmt, Bernd GronerFront. Biosci. (Landmark Ed) 2012, 17(4), 1232–1250; https://doi.org/10.2741/3983(This article belongs to the Special Issue Regulation of signalling in health and disease)13Downloads20Citations41Views
- ArticleUnderstanding TLR9 action in Epstein-Barr virus infectionLudwig Zauner, David NadalFront. Biosci. (Landmark Ed) 2012, 17(4), 1219–1231; https://doi.org/10.2741/3982(This article belongs to the Special Issue Exploiting toll-like receptors to interfere with the B cell response)48Downloads21Citations100Views
- ArticleLocalization status of hepatocellular transporters in cholestasisFernando A Crocenzi, Andres E Zucchetti, Andrea C Boaglio, Ismael R Barosso, ... Marcelo G RomaFront. Biosci. (Landmark Ed) 2012, 17(4), 1201–1218; https://doi.org/10.2741/3981(This article belongs to the Special Issue Experimental and clinical cholestasis)39Downloads38Citations58Views