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Volume | Year
Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.
Ovarian cancer: pathology, biology, and disease models
Daniel G Rosen1, Gong Yang1, Guangzhi Liu1, Imelda Mercado-Uribe1, Bin Chang1, Xue Sherry Xiao1, Jingfang Zheng1, Feng-Xia Xue1, Jinsong Liu1,*
1 Department of Pathology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77005-4095, USA
Academic Editor:Xiaodong Cheng
Front. Biosci. (Landmark Ed) 2009, 14(6), 2089–2102; https://doi.org/10.2741/3364
Published: 1 January 2009
(This article belongs to the Special Issue Cyclic nucleotide signaling and drug discovery)
Epithelial ovarian cancer, which comprises several histologic types and grades, is the most lethal cancer among women in the United States. In this review, we summarize recent progress in understanding the pathology and biology of this disease and in development of models for preclinical research. Our new understanding of this disease suggests new targets for therapeutic intervention and novel markers for early detection of disease.