IMR Press / FBL / Volume 13 / Issue 1 / DOI: 10.2741/2676

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with Frontiers in Bioscience.

Junctional adhesion molecules in angiogenesis
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1 Charter School of Wilmington, University of Delaware, Newark, DE 19716
2 Department of Biological Sciences, University of Delaware, Newark, DE 19716
3 Department of Chemistry and Biochemistry, University of Delaware, Newark, DE 19716
4 Department of Chemical Engineering, University of Delaware, Newark, DE 19716
5 Delaware Biotechnology Institute, University of Delaware, Newark, DE 19716
Front. Biosci. (Landmark Ed) 2008, 13(1), 258–262;
Published: 1 January 2008

The process of new blood vessel formation from pre-existing vessels is known as angiogenesis. This process is important, both during physiological processes such as development and during wound healing, as well as during pathological processes, such as cancer and arthritis. Understanding the molecular mechanism of the regulation of angiogenesis and the identification of the key players involved in this process may help identify new therapeutic targets to combat and control angiogenesis and hence arthritis and cancer. This review focuses on a recently identified novel cell adhesion molecule, Junctional Adhesion Molecule A, and its role in the process of regulating angiogenesis.

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