IMR Press / FBL / Volume 10 / Issue 3 / DOI: 10.2741/1753

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Article
Acquired immunodeficiency syndrome associated lymphoma
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1 Department of Microbiology and Immunology, Brody School of Medicine at East Carolina University, 600 Moye Blvd., Greenville, NC 27834, USA

Academic Editor: Shohreh Amini

Front. Biosci. (Landmark Ed) 2005, 10(3), 2972–2977; https://doi.org/10.2741/1753
Published: 1 September 2005
(This article belongs to the Special Issue AIDS-related malignant diseases)
Abstract

A prior diagnosis of HIV increases the risk of lymphoma between 150 to 250- fold, depending on the subtype, as compared with the risk observed in the general population. The advent of highly active anti-retroviral therapy (HAART) has seen a dramatic reduction in AIDS morbidity and a modest reduction in the incidence of opportunistic infections along with a corresponding reduction in Kaposi's sarcoma. There has not, however, been a clear reduction in the incidence of lymphoma. As HAART therapy continues to improve in the Western world, the morbidity of HIV infection is beginning to shift from AIDS to other associated illness such as lymphoma. The treatment and etiology of lymphoma is a burgeoning issue in the care of HIV positive populations. This review will provide a basic overview of the association between HIV and lymphoma.

Keywords
Infection
Virus
Immune system
Cancer
Tumor
AIDS
HIV
lymphoma
Review
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