IMR Press / FBL / Volume 10 / Issue 3 / DOI: 10.2741/1732

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Article
Inflammation-dependent thrombosis
Show Less
1 Jobst Vascular Research Laboratories, University of Michigan, Ann Arbor, MI 48109-0654, USA
2 Unit for Laboratory Animal Medicine, University of Michigan Medical Center, Ann Arbor, MI

Academic Editor: Arthur Chu

Front. Biosci. (Landmark Ed) 2005, 10(3), 2750–2757; https://doi.org/10.2741/1732
Published: 1 September 2005
(This article belongs to the Special Issue Blood coagulation, inflammation, and thrombosis)
Abstract

Vessel wall endothelial damage initiates a local inflammatory response, which promotes a prothrombotic state driven by tissue factor, adhesion molecules, and pro-inflammatory cytokines. Understanding how natural inflammatory mechanisms promote a procoagulant state, may lead to the development of new pharmacological interventions targeted at thrombosis.

Keywords
Inflammation
Thrombosis
Vascular Disease
Inflammatory Mediators
Thrombogenesis
Tissue Factor
Adhesion Molecules
Microparticles
Review
Share
Back to top