IMR Press / FBL / Volume 10 / Issue 1 / DOI: 10.2741/1527

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Article
Polyoxometalates: introduction to a class of inorganic compounds and their biomedical applications
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1 Laboratoire de Chimie Inorganique et Matériaux Moléculaires, UMR CNRS 7071, Université Pierre et Marie Curie, 4 place Jussieu, 75252 Paris cedex 05, France

Academic Editor: Sadiq Wasfi

Front. Biosci. (Landmark Ed) 2005, 10(1), 275–287; https://doi.org/10.2741/1527
Published: 1 January 2005
Abstract

An increasing number of potential applications for polyoxometalates in human medicine have been reported in the literature. These inorganic complexes are composed of early transition metals (mainly molybdenum, tungsten and vanadium) and oxygen. The present review gives an introduction into the chemistry of these compounds, and an overview of the principal studies of their biological and biochemical effects and their therapeutic potential. The reported antitumoral and antibiotic properties of molybdates and tungstates in vitro and in vivo are compiled and discussed, as are their influences on the blood glucose level in diabetic animals. Aspects of antiviral activities and cell penetration are treated.

Keywords
Polyoxomolybdates
Polyoxotungstates
Polyoxovanadates
Infections
Cancer
Review
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