IMR Press / FBE / Volume 9 / Issue 2 / DOI: 10.2741/E803

Frontiers in Bioscience-Elite (FBE) is published by IMR Press from Volume 13 Issue 2 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Review

Fungal immunomodulatory proteins in the context of biomedicine

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1 Health Faculty, University of Manizales, Street 9a # 19-03, Manizales, Colombia
2 Department, Natural Sciences Faculty, University of Caldas, Street 65 # 26-10, Manizales, Colombia

*Author to whom correspondence should be addressed.

Academic Editor: Octavio Luiz Franco

Front. Biosci. (Elite Ed) 2017, 9(2), 286–306; https://doi.org/10.2741/E803
Published: 1 June 2017
Abstract

Fungi represent a large group of biodiverse microorganisms with potential applications ranging from industrial fields to the treatment for human diseases. A large number of pharmacologically active compounds including terpenoids, polysaccharides and proteins have been derived from these microorganisms. Fungal Immunomodulatory Proteins (FIPs) are a group of active compounds that are being considered for the treatment of asthma, allergy, autoimmune diseases and cancer. Here, we discuss the discovery, heterologous production bioactive mechanisms of action and their potential use in biomedicine.

Keywords
Fungal Immunomodulatory Proteins
FIPs
Recombinant Proteins
Fungal Bioactivity
Review
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