IMR Press / FBE / Volume 7 / Issue 2 / DOI: 10.2741/738

Frontiers in Bioscience-Elite (FBE) is published by IMR Press from Volume 13 Issue 2 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Review
Surgical aspects of live kidney donation: an updated review
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1 Department of Surgery, Division of Transplant Surgery, Erasmus MC, University Medical Center, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands

*Author to whom correspondence should be addressed.

Academic Editor: Frank Dor

Front. Biosci. (Elite Ed) 2015, 7(2), 394–416; https://doi.org/10.2741/738
Published: 1 January 2015
(This article belongs to the Special Issue Transplantation: current developments and future directions)
Abstract

In the early 1990s, live kidney donation regained popularity to meet the demand of kidney transplantation. Significant developments in the field of live kidney donation have established live donation as the prime source of kidney transplants. Nowadays, management is focused on logistic and immunological innovations, and improvements in care of the live donor. However, a flawless surgical procedure in both donor and recipient is a prerequisite for further expansion of live kidney donor transplantation. From a surgical perspective, the introduction of the laparoscopic approach has been a major breakthrough. Less invasive techniques to procure live donor kidneys have been held responsible for a steep increase in the number of live donors. In addition, less invasive imaging, improvements in perioperative care, and novel insights in the follow-up have all improved the care of the live donor. Live kidney donation is developing as the most promising source of renal organs since artificial kidneys, xenografts and stem cell therapy for restoring intrinsic kidney function will probably not find application on a large scale in the near future.

Keywords
Living donors
Surgical techniques
Minimally invasive
Laparoscopic donor nephrectomy
Innovation
Perioperative care
Follow-up
Quality of life
Review
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