IMR Press / FBE / Volume 6 / Issue 2 / DOI: 10.2741/E712

Frontiers in Bioscience-Elite (FBE) is published by IMR Press from Volume 13 Issue 2 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with Frontiers in Bioscience.

Oral lichen planus: a narrative review
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1 Multidisciplinary Department of Medical-Surgical and Odontostomatological Specialties, 6 L. De Crecchio Street, 80138 Naples, Italy

*Author to whom correspondence should be addressed.


Front. Biosci. (Elite Ed) 2014, 6(2), 370–376;
Published: 1 June 2014

Oral Lichen Planus (OLP) is a common disease of unknown aetiology affecting oral mucosae by T-cell mediated chronic inflammation. OLP diagnosis is made by evaluating both clinical and histological criteria. Pharmacological treatment is useful in symptomatic cases. Life-long clinical follow-up is essential, due to low-risk of malignant transformation. In vivo Reflectance Confocal Microscopy (RCM) offers a real-time virtual biopsy of the being tissues and does not require surgical excision nor histopathological processing. RCM was used to capture OLP lesions in order to clinically differentiate them from other clinical entities.

Oral Lichen Planus
Chronic Inflammation
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