IMR Press / FBE / Volume 6 / Issue 2 / DOI: 10.2741/E712

Frontiers in Bioscience-Elite (FBE) is published by IMR Press from Volume 13 Issue 2 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Review
Oral lichen planus: a narrative review
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1 Multidisciplinary Department of Medical-Surgical and Odontostomatological Specialties, 6 L. De Crecchio Street, 80138 Naples, Italy

*Author to whom correspondence should be addressed.

Academic Editor: Alberta Lucchese

Front. Biosci. (Elite Ed) 2014, 6(2), 370–376; https://doi.org/10.2741/E712
Published: 1 June 2014
(This article belongs to the Special Issue Oral diseases: from diagnosis to therapies)
Abstract

Oral Lichen Planus (OLP) is a common disease of unknown aetiology affecting oral mucosae by T-cell mediated chronic inflammation. OLP diagnosis is made by evaluating both clinical and histological criteria. Pharmacological treatment is useful in symptomatic cases. Life-long clinical follow-up is essential, due to low-risk of malignant transformation. In vivo Reflectance Confocal Microscopy (RCM) offers a real-time virtual biopsy of the being tissues and does not require surgical excision nor histopathological processing. RCM was used to capture OLP lesions in order to clinically differentiate them from other clinical entities.

Keywords
Oral Lichen Planus
T-cell
Chronic Inflammation
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