IMR Press / FBE / Volume 5 / Issue 2 / DOI: 10.2741/E649

Frontiers in Bioscience-Elite (FBE) is published by IMR Press from Volume 13 Issue 2 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Article

A potential “tuning” role for the outer hair cells in children with language disorders

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1 Laboratorio de Neuroproteccion, Instituto Nacional de Rehabilitacion, INR- SSa. Mexico D.F.
2 Servicio de Terapia de Lenguaje, Instituto Nacional de Rehabilitacion, INR- SSa. Mexico D.F.
3 Seccion de Posgrado e Investigacion de la Escuela Superior de Medicina del Instituto Politecnico Nacional, Mexico D.F.

*Author to whom correspondence should be addressed.

Front. Biosci. (Elite Ed) 2013, 5(2), 684–696; https://doi.org/10.2741/E649
Published: 1 January 2013
Abstract

The cochlear outer hair cells serve a tuning function, and any dysfunction of their electromotile response can be reflected in language disorders. Otoacoustic emissions can be used to determine any dysfunction of these cells. A set of clinical records was established to register the neurological and auditory functioning in 42 children, followed by assessment with the Wechsler Intelligence Scale for Children (WISC), the Initial Language Test (ILT), the Auditory and Phonetic Discrimination Evaluation (APDE), tests for measuring Brainstem Auditory Evoked Potential (BAEP) and Transient Otoacoustic Emissions (TOAE). Subjects were classified into 3 groups in this study: Control (C; n = 20), Syntactic Phonological Disorder (SPD; n = 17), and those with Phonological Disability (PD; n = 5). BAEP studies showed a clear response when all children were stimulated to 20 dB. TOAE responses displayed clear and significant differences with half-octave band reproducibility for both ears, the largest effect being observed in the right ear. The results that were compared using ANOVA tests, showed that cochlear processing affects the brain language function, playing a critical role in the language phonetic process.

Keywords
Language
Language disorders
Syntactic phonological disorder
Phonological disability
Outer hair cells
Otoacoustic emissions
Whole-Wave- Reproducibility
Half-Octave-Band reproducibility
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