IMR Press / FBE / Volume 5 / Issue 1 / DOI: 10.2741/E622

Frontiers in Bioscience-Elite (FBE) is published by IMR Press from Volume 13 Issue 2 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Review

Regulatory issues in management of chemicals in OECD member countries

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1 Faculty of Technology and Production Management, Moscow State University of Food Production, Volokolamskoe shosse 11, 125080 Moscow, Russia
2 Department of Chemistry, Faculty of Natural Sciences, University of Oriente, Patricio Lumumba s/n, 90500 Santiago de Cuba, Cuba

*Author to whom correspondence should be addressed.

Front. Biosci. (Elite Ed) 2013, 5(1), 375–398; https://doi.org/10.2741/E622
Published: 1 January 2013
Abstract

The chemical risk assessment is determinant for the approval of any kind of chemical. Each aspect of chemical is taken into consideration for the new chemical legislation registration, evaluation, and authorization of chemicals (REACH). However, some improvements can be made in order to select and authorize a chemical. QSAR techniques have been used for the study of several kind of toxicological properties in order to realize a deeper study concerning to risk assessment. For this reason, this work is focused into present a review of chemical legislation policies in the European Union (EU) and in Russia, and changes in chemicals regulations to meet the requirement of REACH. Also, we reported the used of several approaches and chemo- bioinformatics tools applied to QSAR methodologies for the several parameters relative to toxicity and how they can be used for regulatory purposes in risk assessment.

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