IMR Press / FBE / Volume 3 / Issue 3 / DOI: 10.2741/E294

Frontiers in Bioscience-Elite (FBE) is published by IMR Press from Volume 13 Issue 2 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Article
Suppressing allergic immune responses
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1 Department of Medicine and Integrated Department of Immunology, National Jewish Health, University of Colorado Denver School of Medicine, 1400 Jackson Street, K613e, Denver, CO 80206

*Author to whom correspondence should be addressed.

Academic Editor: Hua Huang

Front. Biosci. (Elite Ed) 2011, 3(3), 864–870; https://doi.org/10.2741/E294
Published: 1 June 2011
(This article belongs to the Special Issue Regulation of type-2 immune responses)
Abstract

While most studies are devoted to understanding the activation of cytokine gene transcription, few studies have focused on the silencing of cytokine gene transcription. This review will focus on the molecular mechanisms by which Th1-promoting factors downregulate the Il4 gene.

Keywords
Allergy immune responses
IL-4
airway inflammation
Th1-Promoting Factors
Review
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