IMR Press / FBE / Volume 2 / Issue 3 / DOI: 10.2741/E177

Frontiers in Bioscience-Elite (FBE) is published by IMR Press from Volume 13 Issue 2 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Article
Risk from exposure to arylamines from consumer products and hair dyes
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1 Thomas Platzek Federal Institute for Risk Assessment, Thielallee 88-92, D-14195 Berlin, Germany
Academic Editor:King-Thom Chung
Front. Biosci. (Elite Ed) 2010, 2(3), 1169–1183; https://doi.org/10.2741/E177
Published: 1 June 2010
(This article belongs to the Special Issue Arylamine induced carcinogenesis)
Abstract

Arylamines are widely used for the manufacturing of elastomers, colorants and consumer products. Furthermore they are part of many colorants either as contaminant or as cleavage product. Also many hair dyes are arylamines. Thus consumers are exposed from various sources and products, especially high exposure is contributed by tobacco smoke. Many of the arylamines and colorants derived from them are mutagenic and/or carcinogenic. In contrast, a considerable number of arylamines has been proven to be non hazardous. In other cases exposure was negligible. Insofar the risk due to exposure to arylamines from consumer products has to be assessed case by case considering the toxicological profile and the exposure for each individual substance and product.

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