IMR Press / FBE / Volume 11 / Issue 1 / DOI: 10.2741/E845

Frontiers in Bioscience-Elite (FBE) is published by IMR Press from Volume 13 Issue 2 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Review
Diagnosis of TB: From conventional to modern molecular protocols
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1 Department of Zoology, Mahatma Gandhi Central University (MGCU) Motihari-845401, Bihar, India
2 Department of Zoology, Indira Gandhi National Tribal University (IGNTU), Amarkantak, 484887 (MP), India
Send correspondence to: Pranveer Singh, Department of Zoology, Mahatma Gandhi Central University (MGCU) Motihari-845401, Bihar, India, Tel: 91-9424930522, Fax: 91-9109303833. E-mail: mailpranveer@gmail.com
Front. Biosci. (Elite Ed) 2019, 11(1), 38–60; https://doi.org/10.2741/E845
Abstract

Tuberculosis (TB) is an infectious disease caused by different strains of Mycobacterium tuberculosis complex. TB is a curable infection if diagnosed correctly and timely. Late diagnosis and improper treatment may lead to relapse or its escalation to MDR / XDR-TB. TB with HIV co-infection is difficult to diagnose by conventional set-up. Also, detection of child TB and extrapulmonary TB has its own set of problems and is not straightforward to diagnose. The increasing complexity of TB due to the advent of new circulating strains and invasion to the regions where it was non-existent or thought to be eradicated is putting a severe strain on the health management services and making it an unmanageable pandemic. This increasing complexity has led to the spurt in the development of TB diagnostics platforms. This review focuses on the new emerging technologies that have changed the diagnostics landscape.

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