IMR Press / FBE / Volume 10 / Issue 1 / DOI: 10.2741/E812

Frontiers in Bioscience-Elite (FBE) is published by IMR Press from Volume 13 Issue 2 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Review

Anti-tick vaccines in the omics era

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1 The University of Queensland, Queensland Alliance for Agriculture and Food, Innovation, Queensland Biosciences Precinct, 306 Carmody Rd, St. Lucia Qld, 4067, Australia
2 Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Victoria 3010
3 USDA-ARS, Knipling Bushland US Livestock Insect Research Laboratory, 2700 Fredericksburg Road, Kerrville, TX 78028, USA

*Author to whom correspondence should be addressed.

Front. Biosci. (Elite Ed) 2018, 10(1), 122–136; https://doi.org/10.2741/E812
Published: 1 January 2018
(This article belongs to the Special Issue From tick genetics to genomics)
Abstract

Tick vaccines have been available for more than 20 years. They are useful and effective control agents when used properly. However, no new products have emerged since the Bm86-based Gavac vaccine was commercialized. Acaricide resistance is a problem with no abatement in sight and anti-tick vaccines are likely to be relied upon even more in the coming years. As human medicine and plant agriculture has embraced the various Omics technologies, the search for anti-tick vaccines would be well served to follow; so that new vaccine antigens and adjuvants might be developed to assist tick control programs. However, the simple outward appearance of ticks and their life cycle belies the complexity of their genomes which are computationally challenging to sequence and annotate. We review various Omics research efforts in light of research on anti-tick vaccines.

Keywords
Ticks
Anti-Tick Vaccines
Genomics
Review
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