IMR Press / FBE / Volume 10 / Issue 1 / DOI: 10.2741/E809

Frontiers in Bioscience-Elite (FBE) is published by IMR Press from Volume 13 Issue 2 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Article

Microfluidics technology for drug delivery: A review

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1 School of Engineering and Sciences, Tecnologico de Monterrey, Campus Monterrey Monterrey, Ave. Eugenio Garza Sada 2501, 64849, Monterrey, Nuevo Leon, Mexico
2 Biomedicals Innovation Research Center, Division of Biomedical Engineering, Deparment of Medicine, Brigham and Women’s Hospital, Harvard Medical School, 02139, Boston, Massachusetts, USA
3 Harvard-MIT Division of Health Sciences and Technology, 02139, Cambridge, Massachusetts, USA
4 Microsystems Technologies Laboratories, MIT, 02139, Cambridge, Massachusetts, USA

*Author to whom correspondence should be addressed.

Front. Biosci. (Elite Ed) 2018, 10(1), 74–91; https://doi.org/10.2741/E809
Published: 1 January 2018
(This article belongs to the Special Issue Bioactive molecules from microalgae)
Abstract

Microfluidics is undoubtedly an influential technology that is currently revolutionizing the chemical and biological studies by replicating laboratory bench-top technology on a miniature chip-scale device. In the area of drug delivery science, microfluidics offers advantages, such as precise dosage, ideal delivery, target-precise delivery, sustainable and controlled release, multiple dosing, and slight side effects. These advantages bring significant assets to the drug delivery systems. Microfluidic technology has been progressively used for fabrication of drug carriers, direct drug delivery systems, high-throughput screening, and formulation and immobilization of drugs. This review discusses the recent technological progress, outcomes and available opportunities for the usage of microfluidics systems in drug delivery systems.

Keywords
Microfluidics
Drug delivery
High-throughput screening
Organ-on-a-chip
Cancer cells screening
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