IMR Press / EJGO / Volume 8 / Issue 6 / pii/1987184

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Original Research

The role of combined surgery and radiotherapy in the management of stage Ⅰ and Ⅱ carcinoma of the cervix

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1 Research Assistant and Honorary Senior Registrar in Radiotherapy The Royal Marsden Hospital, Surrey
2 Senior Registrar in Obstetrics and Gynaecology - St. Belier Hospital, Carshalton, and the Royal Marsden Hospital, London and Surrey
3 Consultant Radiotherapist - The Royal Marsden Hospital, Surrey
Eur. J. Gynaecol. Oncol. 1987, 8(6), 578–584;
Published: 10 December 1987

The results are presented of 100 patients with stage I B, II A or II B carcinoma of the cervix treated by combined surgery and radiotherapy. The actuarial five year survival rates for FIGO stage I B (74 patients) was 85%, for selected stage II A (8 patients) 100%, and for se­lected early stage II B (18 patients) 72%. Within FIGO stage I B the five year survival for pa­tients with negative nodes was 93% and for those with positive nodes 36%. The radiotherapy complication rate for patients treated with pre-operative radiotheiapy followed by Wertheim's hys­terectomy was 5%. However, when additional post-operative radiotherapy was given, the compli­cation rate was 60%. It is concluded that pre-operative intracavitary radiotherapy followed by Wertheim's hysterectomy is suitable treatment for early-stage disease with negative nodes, but is unsatisfactory treatment for poor risk patients requiring additional post-operative radiotherapy, as their survival rate is poor and the complication rate is high. 

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