IMR Press / EJGO / Volume 7 / Issue 2 / pii/1986019

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Original Research

Regional chemotherapy by a totally infusion pump preceding radiotherapy in advanced cervical carcinoma: a preliminary report

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1 Institute of Radiology Depart. Radiot. Oneal, Università Cattolica Sacra Cuore, Roma, Italy
2 Institute of Obstetrics and Gynaecology, Università Cattolica Sacra Cuore, Roma, Italy
3 Institute of Pathology Surgery, Università Cattolica Sacra Cuore, Roma, Italy
Eur. J. Gynaecol. Oncol. 1986, 7(2), 97–108;
Published: 10 June 1986
Abstract

The Authors report the preliminary results of a prospective study on intra-arterial chemotherapy and radiotherapy of advanced cervix carcinoma. The drugs were delivered by a totally implanted Infusaid Model 400 pump and patients received cyclic therapy consisting of Cis-Platinum, Methotrexate and Bleomycin. The catheter tips were positioned during a laparotomy in the hypogastric arteries with sutures and the pump was implanted in a subcutaneous pouch in the abdomen. After chemotherapy all patients had radiotherapy. Five patients entered in the study. Preliminary results suggest that long-term intra-arterial infusion chemotherapy for the treatment of advanced cervix carcinoma is practical for many patients. Two of five patients, after intra-arterial chemotherapy and radiotherapy, had radical hysterectomy.

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