IMR Press / EJGO / Volume 7 / Issue 1 / pii/1986004

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Original Research

A clinico-pathological evaluation of parametrial involvement of deep invasive carcinoma of the uterine cervix

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1 Department of Obstetrics and Gynecology School of Medicine, University of Tokushima Kuramotocho, Tokushima, Japan
Eur. J. Gynaecol. Oncol. 1986, 7(1), 18–27;
Published: 10 February 1986

Whole parametrial tissues from 235 patients with deep invasive carcinoma (>5 mm in depth) of the cervix were systematically examined for involvement of cancer. Significantly higher incidences were observed in patients over 60 years of age than those of other age groups, and in patients with either adenocarcinoma or adenosquamous carcinoma than those with squamous cell carcinoma. The parametria were considered not to be the base camps but the pathways for pelvic node metastasis because of extranodal situation of most of small cancer nests in parametria, similar extent of incidence of metastases between parametrial and other pelvic nodes, and discrepancy in the incidence between parametrial involvement and ipsilateral nodal metastases. The relative 5-year survival rate was no less than 67 % even in patients with parametrial involvement and/or pelvic node metastases. This rate seems to suggest some roles of these tissues as a barrier against extrapelvie expansion of cancer.

Cervical carcinoma
Radical surgery
Parametrial involvement
Node metastasis
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