IMR Press / EJGO / Volume 6 / Issue 3 / pii/1985045

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Original Research

Chlamydia trachomatis infection monitoring with cytomorphology, direct immunofluorescence and "In vitro" Growth method

Show Less
1 Research Assistent, Department of Human Biopathology, Department of Human Biopathology <<La Sapienza>> University, Rome, Italy
2 Recipient of a fellowship from Institute of Experimental Medicine, Section for Infections Diseases, Rome, Italy
3 Associate Professor Department of Obstetric and Gynecology, Department of Human Biopathology <<La Sapienza>> University, Rome, Italy
4 Professor of Clinical Pediatrics - Progetto finalizzato Institute of Experimental Medicine, Section for Infections Diseases, Rome, Italy
Eur. J. Gynaecol. Oncol. 1985, 6(3), 192–199;
Published: 10 October 1985
Abstract

The increased occurrence of genital infections from Chlamydia trachomatis (Ct) suggested the need for a simple, rapid, sensitive method for detection of Ct. The purpose of the present study was to select symptomatic or asymptomatic women through two fast screenings: Pap-test and direct immunofluorescence (IF) test with monoclonal antibody. From 1,816 cervical cytology samples, 32 (1.76%) were selected for intracytoplasmic inclu­sions pathognomonic of Ct infection. Only 19 women underwent a check-up. The direct IF gave positive results in ten cases out of 19 (52.63%), and culture in eleven (57.89%). A correlation was made between the direct IF test and culture and also between cytologic and colposcipc findings. We thus cocnlude that direct IF, for its specificity, sensitivity, easy execution and low cost, could be currently utilized when clinical signs or Pap smears are suggestive of Ct infections. 

Share
Back to top