IMR Press / EJGO / Volume 5 / Issue 2 / pii/1984015

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Open Access Original Research

Residual tumor following radiotherapy for locally advanced carcinomas of the uterine cervix prognostic Significance

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1 Division of Gynecologic Oncology, Department of Obstetrics and Gynecology Tufts University School of Medicine, New England Medical Center Hospitals Boston, Massachusetts (USA)
Eur. J. Gynaecol. Oncol. 1984, 5(2), 90–94;
Published: 10 June 1984
Abstract

Over a five-year period from 1977 to 1982, 120 patients with locally advanced carcinomas of the uterine cervix were surgically staged by lymphadenectomy and laparotomy. Radiotherapy was then administered according to the pelvic extent of disease, and all patients underwent extrafascial total hysterectomy with adnexectomy at ten weeks after completing radiation therapy. The presence or absence of residual tumor in the hysterectomy specimen appeared to be an important prognostic factor in treatment success or failure. Patients with no residual tumor were found to have an exellent prognosis. Those with residual tumor clear of the resection margins were at risk for distant, metastases. Only one survivor was noted in the group of patients in whom the margins of resection were involved with tumor, nearly all of these patients dying from local recurrences. Major operative morbidiy in the series was minimal, and consisted of a single ureterovaginal fistula, which required urinary diversion.

Keywords
Carvical cancer
Radiotherapy
Prognosis
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