IMR Press / EJGO / Volume 41 / Issue 6 / DOI: 10.31083/j.ejgo.2020.06.2174
Open Access Review
Endometrial adenocarcinoma arising in adenomyosis: case report and review of literature
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1 Department of Obstetrics and Gynecology, Kyung Hee University Hospital at Gangdong, School of Medicine, Kyung Hee University, 892 Dongnam-ro, Gangdong-gu, Seoul 05278, Korea
Eur. J. Gynaecol. Oncol. 2020, 41(6), 858–862;
Submitted: 21 June 2020 | Accepted: 12 August 2020 | Published: 15 December 2020

Adenomyosis is a common benign gynecological condition in women of reproductive age. While endometrial cancer co-existing with adenomyosis is common, endometrial carcinoma arising from endometrial cells within adenomyosis (EC-AIA) is rare. We present an unusual case of EC-AIA in a 62-year-old woman with no clinical symptoms. EC-AIA should be considered as a different diagnosis from concurrent endometrial cancer and adenomyosis. EC-AIA should also be considered in adenomyosis patients with intact endometrium and vaginal bleeding and in those with a history of adenomyosis at reproductive age regardless of the occurrence of vaginal bleeding. Periodic follow-up is recommended in women diagnosed with adenomyosis at reproductive age.

Endometrial cancer
Endometrial adenocarcinoma
Figure 1.
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