IMR Press / EJGO / Volume 41 / Issue 3 / DOI: 10.31083/j.ejgo.2020.03.4672
Open Access Case Report
Intrapelvic low grade leiomyosarcoma with good prognosis
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1 Department of Gynecology and Obstetrics, Baskent University, Ankara, Turkey
2 Department of Pathology, Dokuz Eylul University, Izmir 35000, Turkey
3 Department of Gynecology and Obstetrics, Dokuz Eylul University, Izmir 35000, Turkey
4 Department of Internal Disease, Dokuz Eylul University, Izmir 35000, Turkey
5 Department of Gynecology and Obstetrics, Kent Hospital, Izmir 35000, Turkey
Eur. J. Gynaecol. Oncol. 2020, 41(3), 468–470; https://doi.org/10.31083/j.ejgo.2020.03.4672
Submitted: 15 January 2018 | Accepted: 17 October 2019 | Published: 15 June 2020
Abstract

Soft tissue sarcomas (STS) are rare mesenchymal neoplasms arising from nonepithelial connective tissue origins. Retroperitoneal Soft tissue sarcomas may be primary tumours or metastases especially from the uterus. Here, the authors present a case of intrapelvic leiomyosarcoma treated with hormonotherapy after surgery. A 40-year-old multiparous woman was admitted to the hospital with abdominal pain. Abdominopelvic ultrasound was performed, and an uncircmuscribed mass was seen in the Douglas pouch. At laparotomy, a tumour measuring 7 cm in size, appearing as a sarcoma attached to the sigmoid colon serosa was found. The tumour was positive with H-caldesmon, actin, desmin, oestrogen and progesterone receptors (ER/PR). The patient with a diagnosis of low-grade intrapelvic leiomyosarcoma received adjuvant hormonotherapy after adjuvant radiotherapy. She is doing well without disease recurrence during a two-year follow-up period. Despite contradictory data according to recent limited investigations, the present authors suggest that ER and PR should be routinely quantified in STS by immunohistochemical methods, and it should be kept in mind that hormonotherapy may be a beneficial option.

Keywords
Intrapelvic leiomyosarcoma
Tumour receptors
Hormonotherapy
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