IMR Press / EJGO / Volume 41 / Issue 2 / DOI: 10.31083/j.ejgo.2020.02.5226
Open Access Review
Should we search for high-risk HPV in vaginal vault Pap smear after hysterectomy due to CIN2+?
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1 Serviço de Ginecologia e Obstetrìcia do Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal
2 Serviço de Ginecologia e Obstetrìcia do Centro Hospitalar Tâmega e Sousa, Penafiel, Portugal
Eur. J. Gynaecol. Oncol. 2020, 41(2), 157–162;
Published: 15 April 2020

Women with a history of hysterectomy due to malignant or premalignant cervical disease are currently submitted to tight surveillance, which consists of vaginal Pap tests for as long as 20 years in the late follow-up period. Nevertheless, published literature has concluded that vaginal Pap screening has a very low detection yield. Also, these recommendations are almost entirely from an era before high-risk HPV (hrHPV) DNA testing. The authors’ aim is to review these women’s current management and share the scarce recommendations available for the management of abnormal vaginal Pap and/or adjunctive hrHPV DNA tests in these patients.

Vaginal Pap tests
hrHPV vaginal testing
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